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Latest updates to the ARV-471 & Palbociclib in ER+/HER2- mBC Clinical Trial page

  1. Check
    6 days ago
    No Change Detected
  2. Check
    13 days ago
    Change Detected
    Summary
    Updated study details add a core biopsy requirement for ER IHC and PD testing, and introduce dose escalation with an RP2D plus a palbociclib combination cohort. ARV-471 dosing for Parts A and B is now specified as QD or BID for 28-day cycles, with pharmacokinetic endpoints (AUC) included.
    Difference
    0.8%
    Check dated 2026-02-11T14:15:53.000Z thumbnail image
  3. Check
    21 days ago
    Change Detected
    Summary
    Added a government funding lapse notice indicating NIH Clinical Center status and updated the system revision from v3.4.0 to v3.4.1. To avoid being alerted by small changes, set an alert condition by clicking below.
    Difference
    0.4%
    Check dated 2026-02-04T10:25:06.000Z thumbnail image
  4. Check
    28 days ago
    Change Detected
    Summary
    The page now shows the glossary and new metadata fields (Last Update Submitted that Met QC Criteria, Last Update Posted, No FEAR Act Data) with revision updated to v3.4.0; older metadata fields and the previous revision v3.3.4 were removed.
    Difference
    0.2%
    Check dated 2026-01-28T06:23:53.000Z thumbnail image
  5. Check
    42 days ago
    Change Detected
    Summary
    Revision: v3.3.4 was added and Revision: v3.3.3 was removed.
    Difference
    0.0%
    Check dated 2026-01-14T03:19:05.000Z thumbnail image
  6. Check
    63 days ago
    Change Detected
    Summary
    The page now includes a consolidated Locations section listing California, Connecticut, Florida, Illinois, Massachusetts, Michigan, Missouri, New Jersey, New York, North Carolina, Tennessee, and Washington, with a new revision tag v3.3.3. The previous state-specific location sections and the HHS Vulnerability Disclosure link have been removed, and the Revision tag changed from v3.3.2.
    Difference
    1%
    Check dated 2025-12-23T20:41:39.000Z thumbnail image
  7. Check
    92 days ago
    Change Detected
    Summary
    Added a new Revision: v3.3.2 and removed Revision: v3.2.0 in the page's release notes area.
    Difference
    0.0%
    Check dated 2025-11-25T10:48:38.000Z thumbnail image

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