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Latest updates to the AVA6000 in Solid Tumours Clinical Trial page

  1. Check
    7 days ago
    Change Detected
    Summary
    The study page appears unchanged in core content such as eligibility criteria and locations; To avoid being alerted by small changes, set an alert condition by clicking below.
    Difference
    0.0%
    Check dated 2026-02-18T04:08:00.000Z thumbnail image
  2. Check
    14 days ago
    Change Detected
    Summary
    Added details of the Phase 1a 3+3 dose-escalation design for AVA6000 with Q3W and Q2W schedules and the Phase 1b dose expansion with an RDE-1 cohort to identify the optimal biologic dose. It also notes AVA6000 as a FAP-activated doxorubicin and updates the cardiac safety assessment to include cumulative exposure to doxorubicin.
    Difference
    1%
    Check dated 2026-02-11T02:10:06.000Z thumbnail image
  3. Check
    21 days ago
    Change Detected
    Summary
    Added a site-wide notice about government funding status and NIH CC operations, and updated CMS to version v3.4.1. The previous CMS version v3.4.0 was removed.
    Difference
    0.4%
    Check dated 2026-02-03T23:50:47.000Z thumbnail image
  4. Check
    28 days ago
    Change Detected
    Summary
    Adds a glossary display and new study-record metadata fields: Last Update Submitted that Met QC Criteria and Last Update Posted, along with No FEAR Act Data and a Revision: v3.4.0 note. Removes older QC-related labels (Last Update Submitted that met QC Criteria, Last Update Posted (Estimated), No FEAR Act data, Revision: v3.3.4) and, to avoid being alerted by small changes, set an alert condition by clicking below.
    Difference
    0.2%
    Check dated 2026-01-27T23:58:55.000Z thumbnail image
  5. Check
    42 days ago
    Change Detected
    Summary
    The update is a minor revision from v3.3.3 to v3.3.4 and does not modify substantive study information. To avoid being alerted by small changes, set an alert condition by clicking below.
    Difference
    0.0%
    Check dated 2026-01-13T19:23:08.000Z thumbnail image
  6. Check
    64 days ago
    Change Detected
    Summary
    Added study sites in New York, Texas, and Washington and included Dr Jennifer Specht as Principal Investigator. Updated TNBC eligibility to allow any prior therapy with BRCA wild-type and removed the previous site list and the TNBC criteria restricting to up to 3 lines of prior therapy and BRCA PD-L1 negative.
    Difference
    0.7%
    Check dated 2025-12-23T08:38:07.000Z thumbnail image

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