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- CheckyesterdayChange DetectedThe page now displays a 'Last Update Posted' field and the '(Estimated)' label has been removed, changing how updates are labeled but not altering substantive trial information. To avoid being alerted by small changes, set an alert condition by clicking below.SummaryDifference0.0%

- Check8 days agoChange DetectedAdded Phase II melanoma cohort eligibility expansion for NUC-7738 + pembrolizumab: metastatic cutaneous melanoma patients with measurable disease who progressed on up to two prior lines, with at least one PD-1/PD-L1-containing regimen. The progression-in-last-12-months constraint was removed, and the record shows Revision: v3.3.4 with Last Update Posted 2026-01-12.SummaryDifference0.7%

- Check16 days agoNo Change Detected
- Check30 days agoChange DetectedFooter now displays Revision: v3.3.3, and the HHS Vulnerability Disclosure link and Revision: v3.3.2 have been removed; To avoid being alerted by small changes, set an alert condition by clicking below.SummaryDifference0.1%

- Check59 days agoChange DetectedRevision: v3.3.2 was added and Revision: v3.2.0 was removed on the page. This is a metadata update and does not affect the study information presented.SummaryDifference0.0%

- Check66 days agoChange DetectedThe government funding status notice was removed from the page. No other substantive study details were altered; To avoid being alerted by small changes, set an alert condition by clicking below.SummaryDifference0.3%

- Check88 days agoChange DetectedCore study details and outcomes remain unchanged; the new screenshot shows only superficial formatting changes to layout and typography.SummaryDifference0.4%

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