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Latest updates to the ORION-3 Extension Trial: Inclisiran in Cardiovascular Disease Clinical Trial page

  1. Check
    2 days ago
    No Change Detected
  2. Check
    10 days ago
    Change Detected
    Summary
    Footer update: Revision: v3.3.3 is now displayed and the HHS Vulnerability Disclosure link has been removed. This change does not affect study results or page functionality.
    Difference
    0.0%
    Check dated 2025-12-18T08:49:45.000Z thumbnail image
  3. Check
    19 days ago
    No Change Detected
  4. Check
    26 days ago
    Change Detected
    Summary
    Minor version update applied: Revision from v3.3.1 to v3.3.2 with no visible changes to page content or layout. To avoid being alerted by small changes, set an alert condition by clicking below.
    Difference
    0.0%
    Check dated 2025-12-01T18:59:25.000Z thumbnail image
  5. Check
    34 days ago
    Change Detected
    Summary
    Added detailed numeric outcomes for ORION-3 (mean with 95% CI, ug/L, Day 30/360/720/1440) for LDL-C and PCSK9 in the Inclisiran-only arm, plus expanded participant counts and time-frame descriptions; updated PubMed publication notes to replace older wording.
    Difference
    0.2%
    Check dated 2025-11-24T15:13:49.000Z thumbnail image
  6. Check
    41 days ago
    Change Detected
    Difference
    0.4%
    Check dated 2025-11-17T08:11:43.000Z thumbnail image
  7. Check
    58 days ago
    Change Detected
    Summary
    The ORION-3 results section has been updated to include long-term efficacy and safety data, with LDL-C changes over time and adverse events across treatment arms. This update reflects the four-year open-label extension of ORION-1 and the associated extended follow-up results.
    Difference
    0.0%
    Check dated 2025-10-31T01:52:48.000Z thumbnail image
  8. Check
    65 days ago
    Change Detected
    Summary
    No significant additions or deletions were detected on the page; the study results information and layout appear unchanged.
    Difference
    0.0%
    Check dated 2025-10-24T00:11:57.000Z thumbnail image

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