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Latest updates to the ORION-3 Extension Trial: Inclisiran in Cardiovascular Disease Clinical Trial page

  1. Check
    7 days ago
    No Change Detected
  2. Check
    14 days ago
    No Change Detected
  3. Check
    24 days ago
    No Change Detected
  4. Check
    31 days ago
    Change Detected
    Summary
    Footer update: Revision: v3.3.3 is now displayed and the HHS Vulnerability Disclosure link has been removed. This change does not affect study results or page functionality.
    Difference
    0.0%
    Check dated 2025-12-18T08:49:45.000Z thumbnail image
  5. Check
    48 days ago
    Change Detected
    Summary
    Minor version update applied: Revision from v3.3.1 to v3.3.2 with no visible changes to page content or layout. To avoid being alerted by small changes, set an alert condition by clicking below.
    Difference
    0.0%
    Check dated 2025-12-01T18:59:25.000Z thumbnail image
  6. Check
    55 days ago
    Change Detected
    Summary
    Added detailed numeric outcomes for ORION-3 (mean with 95% CI, ug/L, Day 30/360/720/1440) for LDL-C and PCSK9 in the Inclisiran-only arm, plus expanded participant counts and time-frame descriptions; updated PubMed publication notes to replace older wording.
    Difference
    0.2%
    Check dated 2025-11-24T15:13:49.000Z thumbnail image
  7. Check
    62 days ago
    Change Detected
    Difference
    0.4%
    Check dated 2025-11-17T08:11:43.000Z thumbnail image
  8. Check
    79 days ago
    Change Detected
    Summary
    The ORION-3 results section has been updated to include long-term efficacy and safety data, with LDL-C changes over time and adverse events across treatment arms. This update reflects the four-year open-label extension of ORION-1 and the associated extended follow-up results.
    Difference
    0.0%
    Check dated 2025-10-31T01:52:48.000Z thumbnail image
  9. Check
    86 days ago
    Change Detected
    Summary
    No significant additions or deletions were detected on the page; the study results information and layout appear unchanged.
    Difference
    0.0%
    Check dated 2025-10-24T00:11:57.000Z thumbnail image

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