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Latest updates to the SNDX-5613 in R/R Leukemias: Clinical Trial page

  1. Check
    4 days ago
    Change Detected
    Summary
    Phase 2 expansion cohorts increased from 3 to 4 with the addition of Cohort 2D (HOX/MEIS upregulation leukemias, including KMT2Ar, NPM1m, and NUP98r) and the enrollment target is updated to 447. Key inclusion/exclusion criteria were added or revised (e.g., CNS prophylaxis allowed, concurrent cytoreductive therapies permitted, and other drug interactions) to reflect new eligibility and concomitant therapy guidelines.
    Difference
    1%
    Check dated 2026-02-20T17:03:13.000Z thumbnail image
  2. Check
    11 days ago
    Change Detected
    Summary
    The page shows a minor revision update from v3.4.1 to v3.4.2 with no observable changes to study content. To avoid being alerted by small changes, set an alert condition by clicking below.
    Difference
    0.0%
    Check dated 2026-02-13T12:52:56.000Z thumbnail image
  3. Check
    19 days ago
    Change Detected
    Summary
    A new 2026 publication reference was added to Publications (Garcia MB et al., High-throughput proteomic profiling to evaluate differentiation syndrome with menin inhibition, Mol Cell Proteomics, 2026 Jan 30:101522, Online ahead of print) and the page revision was updated from v3.4.0 to v3.4.1. To avoid being alerted by small changes, set an alert condition by clicking below.
    Difference
    0.0%
    Check dated 2026-02-05T15:36:28.000Z thumbnail image
  4. Check
    27 days ago
    Change Detected
    Summary
    Added a glossary toggle and new metadata items (Last Update Submitted that Met QC Criteria, No FEAR Act Data, Revision: v3.4.0); removed the older QC-related date, No FEAR Act data, and Revision: v3.3.4.
    Difference
    0.1%
    Check dated 2026-01-29T06:53:10.000Z thumbnail image
  5. Check
    34 days ago
    Change Detected
    Summary
    The 'Last Update Posted' entry changed from 'Estimated' (2025-11-07) to a concrete date (2025-11-10) in the Study Record Dates section.
    Difference
    0.1%
    Check dated 2026-01-22T04:51:41.000Z thumbnail image
  6. Check
    41 days ago
    Change Detected
    Summary
    Revision: v3.3.4 was published, replacing the previous v3.3.3. There is no visible impact on study details, eligibility, or results.
    Difference
    0.0%
    Check dated 2026-01-15T02:45:26.000Z thumbnail image

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