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Latest updates to the SNDX-5613 in R/R Leukemias: Clinical Trial page

  1. Check
    3 days ago
    Change Detected
    Summary
    Added the March 2026 Mol Cell Proteomics publication 'High-Throughput Proteomic Profiling to Evaluate Differentiation Syndrome With Menin Inhibition' (doi:10.1016/j.mcpro.2026.101522). Removed the January 2026 'Online ahead of print' listing for the same article.
    Difference
    0.0%
    Check dated 2026-04-04T05:44:40.000Z thumbnail image
  2. Check
    10 days ago
    No Change Detected
  3. Check
    17 days ago
    Change Detected
    Summary
    The study record was updated to add numerous sites and investigators with updated contact details, and several former contacts were removed.
    Difference
    4%
    Check dated 2026-03-20T20:18:29.000Z thumbnail image
  4. Check
    24 days ago
    No Change Detected
  5. Check
    31 days ago
    Change Detected
    Summary
    Added a new publication citation (Mol Cell Proteomics, 2026) and updated the page revision to v3.4.3; the prior citation was removed (v3.4.2).
    Difference
    0.0%
    Check dated 2026-03-06T18:07:16.000Z thumbnail image
  6. Check
    45 days ago
    Change Detected
    Summary
    Phase 2 expansion cohorts increased from 3 to 4 with the addition of Cohort 2D (HOX/MEIS upregulation leukemias, including KMT2Ar, NPM1m, and NUP98r) and the enrollment target is updated to 447. Key inclusion/exclusion criteria were added or revised (e.g., CNS prophylaxis allowed, concurrent cytoreductive therapies permitted, and other drug interactions) to reflect new eligibility and concomitant therapy guidelines.
    Difference
    1%
    Check dated 2026-02-20T17:03:13.000Z thumbnail image
  7. Check
    52 days ago
    Change Detected
    Summary
    The page shows a minor revision update from v3.4.1 to v3.4.2 with no observable changes to study content. To avoid being alerted by small changes, set an alert condition by clicking below.
    Difference
    0.0%
    Check dated 2026-02-13T12:52:56.000Z thumbnail image
  8. Check
    60 days ago
    Change Detected
    Summary
    A new 2026 publication reference was added to Publications (Garcia MB et al., High-throughput proteomic profiling to evaluate differentiation syndrome with menin inhibition, Mol Cell Proteomics, 2026 Jan 30:101522, Online ahead of print) and the page revision was updated from v3.4.0 to v3.4.1. To avoid being alerted by small changes, set an alert condition by clicking below.
    Difference
    0.0%
    Check dated 2026-02-05T15:36:28.000Z thumbnail image

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