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Latest updates to the Soticlestat in Rare Epilepsies Clinical Trial page

  1. Check
    2 days ago
    Change Detected
    Summary
    The ENDYMION 1 study (NCT03635073) was terminated due to negative results from related phase 3 studies, and supplementary data were deemed unnecessary. The record now reflects the termination and includes posted results and QC date updates in 2026.
    Difference
    0.1%
    Check dated 2026-04-04T06:09:20.000Z thumbnail image
  2. Check
    9 days ago
    Change Detected
    Summary
    Added 'Severe myoclonic epilepsy in infancy' to the Conditions section and removed 'Dravet syndrome'.
    Difference
    0.0%
    Check dated 2026-03-28T02:59:32.000Z thumbnail image
  3. Check
    16 days ago
    Change Detected
    Summary
    Added a Results Posted entry with detailed long-term safety and outcome data (ECG, vital signs, labs, seizures, and behavioral measures) and related documentation; removed the prior Results Submitted content and associated metrics.
    Difference
    4%
    Check dated 2026-03-21T00:36:32.000Z thumbnail image
  4. Check
    24 days ago
    No Change Detected
  5. Check
    31 days ago
    Change Detected
    Summary
    Revision label updated from v3.4.2 to v3.4.3 on the page.
    Difference
    0.0%
    Check dated 2026-03-06T17:54:06.000Z thumbnail image
  6. Check
    38 days ago
    Change Detected
    Summary
    The study status is updated to Terminated, with notes indicating closure due to external results; the record now reflects that this study is no longer active.
    Difference
    0.1%
    Check dated 2026-02-27T18:49:28.000Z thumbnail image
  7. Check
    45 days ago
    Change Detected
    Summary
    Study status updated to Terminated with a justification that supplementary data is no longer necessary following negative results from related trials; the study is now closed.
    Difference
    0.0%
    Check dated 2026-02-20T15:40:40.000Z thumbnail image

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