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    Added new study identifiers KEYNOTE-E10, MK-3475-E10, and jRCT2061220066; removed MK3475-C73 and updated the registry labeling.
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    Added detailed primary objectives (PFS/OS) and endpoint definitions (ORR, DoR, DCR, PFS, OS) along with TROP2 NMR assessment and IPD data-sharing information. Removed or altered several earlier endpoint definitions, time frames, and explicit eligibility criteria.
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